One of the ironies of our political system is that you don't have to be very smart to be a successful politician.

Case in point; Joe Biden. There have been dumber Vice Presidents in our history, but few have had the stupidity - and hubris - to open their mouths and try to disprove that statement on almost a daily basis.

Occasionally, however, Biden gets it right, as ABC's Karen Travers reports:

Vice President Joe Biden said today that if Democrats were to lose 35 House seats they currently hold in traditionally Republican districts, it would mean doomsday for President Obama's agenda.

Biden said Republicans are pinning their political strategy on flipping these seats.

"If they take them back, this the end of the road for what Barack and I are trying to do," the vice president said at a fundraiser for Rep. Gabrielle Giffords (D-AZ) today in Greenville, Delaware.

Republicans need to pick up 40 seats next November to take back control of the House.

There are 49 seats currently held by Democrats in districts that Sen. John McCain (R-Ariz) won in last year's presidential election.

Biden said these House seats are Republicans "one shot" at breaking the Obama administration's agenda. But if Democrats can hold on to those seats, "the dam is going to break," he said, and a new era of bipartisanship will begin.

"All the hidden Republicans that don't have the courage to vote the way they want to vote because of pressure from the party ... it will break the dam and you will see bipartisanship," Biden said.