Caroline Glick, frequent contributor to the Jerusalem Post, writing at The Corner thinks so:

From an Israeli perspective, Pres. Barack Obama's speech today in Cairo was deeply disturbing. Both rhetorically and programmatically, Obama's speech was a renunciation of America's strategic alliance with Israel.

Rhetorically, Obama's sugar coated the pathologies of the Islamic world - from the tyranny that characterizes its regimes, to the misogyny, xenophobia, Jew hatred, and general intolerance that characterizes its societies. In so doing he made clear that his idea of pressing the restart button with the Islamic world involves erasing the moral distinctions between the Islamic world and the free world.

In contrast, Obama's perverse characterization of Israel - of the sources of its legitimacy and of its behavior - made clear that he shares the Arab world's view that there is something basically illegitimate about the Jewish state.

Just as abominably, Obama compared Israel to Southern slave owners and Palestinians to black slaves in the antebellum south. He used the Arab euphemism "resistance" to discuss Palestinian terrorism, and generally ignored the fact that every Palestinian political faction is also a terrorist organization.

In addition to his morally outrageous characterization of Israel and factually inaccurate account of its foundations, Obama struck out at the Jewish state through the two policies he outlined in his address. His first policy involves coercing Israel into barring all Jewish construction in Judea and Samaria (otherwise known as the West Bank), and Jerusalem.